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Joint Health - Glucosamine Sulfate 500 mg Tabs (90 Count)

Availability: In stock
Stock Number :JNT-104-ST-090
  • Bone, Joint, and Musculoskeletal
  • Quick Notes:

    • Helps replenish and maintain nutrients for healthy joint function and mobility.
    • Glucosamine supports healthy cartilage tissue and maintain joint strength.

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    List Price: $22.78

    Price: $13.64


    Product Information

    Quick Notes:

    • Helps replenish and maintain nutrients for healthy joint function and mobility!
    • Glucosamine supports healthy cartilage tissue and maintain joint strength!
    • Building block of joint tissue!
    • Glucosamine sulfate is a natural seafood extract (from crab shells)!
    • Each tablet contains 500 mg of high quality glucosamine sulfate!
    • Potassium supports cellular fluid balance!


    Glucosamine Sulfate:

    Glucosamine sulfate is the most biologically absorbable variant of glucosamine and is used to promote healthy joints. It is an amino polysaccharide, formed by combining the amino acid - glutamine and glucose. Glucosamine is produced in the body and takes part in the formation of cartilage, ligaments, tendons, and collagen. Glucosamine also supports the health of tissues and organs.

    Over the long term Glucosamine may be more effective at managing joint health because it continues to work weeks after supplementation has been discontinued. On the other hand, pain killer’s effects tend to wear off quickly as they have short half-lives or are excreted from the body within hours. Research indicates that Glucosamine may also help to relieve the stiffness, pain, and swelling associated with joint disorders.

    Approximately 70 countries worldwide authorize Glucosamine as a ‘treatment’ for persons with mild to moderately severe joint disorders.

    Research indicates:

    • May support a healthy inflammation response
    • May help alleviate progressive joint damage
    • Shown to speed healing of joint sprains and muscle strains
    • Commonly used by medical practitioners as an over the counter treatment of joint disorders
    • May promote healthy healing and lessen scarring from wounds or surgery


    Glucosamine Sulfate

    Joint Health


    Suggested Use: Take 1 tablet up to three times daily with meals


    Keep in a cool, dry place.

    Allergy Warnings:

    • Everyone has unique body chemistry. All patients should be aware of potential drug and supplement interaction. You are encouraged to consult with your primary health care professional before taking any supplement product.

    • Contains ingredient derived from shellfish (crab and/or shrimp).


    • Everyone has unique body chemistry. All patients should be aware of potential drug and supplement interaction. You are encouraged to consult with your primary health care professional before taking any supplement product.

    • If you are taking blood thinning medications, NSAIDs (non-steroidal anti-inflammatory drugs), medication for diabetes, or being treated for cancer please consult with your primary health care professional before taking this product.

    • Glucosamine Sulfate may increase the risk of developing insulin resistance and could decrease the metabolic actions of insulin. Persons that have diabetes should consult a health care practitioner prior to using products containing Glucosamine Sulfate

    • In rare cases mild digestive distress has been reported by those taking Glucosamine Sulfate, taking with a meal typically alleviates this response.

    Pregnancy Warning:

    If you are pregnant, nursing, have any health condition, or are taking any medications please consult with your health care practitioner before using this product.

    Keep out of reach of children.


    • The following scientific literature references, articles, and statements have not been evaluated by the Food and Drug Administration (FDA).
    • This product is not intended to treat, cure or prevent any disease.
    • Information about this product is intended for your general knowledge only and is not a substitute for professional medical advice or treatment.

    1. Rozendaal RM, Koes BW, van Osch GJ, et al. Effect of glucosamine sulfate on hip osteoarthritis: a randomized trial. Ann Intern Med. 2008;148:268-277.

    2. Ostergaard K, Hviid T, Hyllested-Winge JL. The effect of glucosamine sulphate on the blood levels of cholesterol or triglycerides—a clinical study. Ugeskr Laeger.2007;169:407-410.

    3. Arendt-Nielsen L, Weidner M, Bartholin D, Rosetzsky A. A double-blind randomized placebo controlled parallel group study evaluating the effects of ibuprofen and glucosamine sulfate on exercise induced muscle soreness. J Musculoskelet Pain. 2007;15:21-28.

    4. Ostojic SM, Arsic M, Prodanovic S, et al. Glucosamine administration in athletes: effects on recovery of acute knee injury. Res Sports Med. 2007;15:113-124.

    5. Bruyere O, Pavelka K, Rovati LC, et al. Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis: evidence from two 3-year studies. Menopause. 2004;11:138-143.

    6. Braham R, Dawson B, Goodman C. The effect of glucosamine supplementation on people experiencing regular knee pain. Br J Sports Med. 2003;37:45-49.

    7. Hughes R, Carr A. A randomized, double-blind, placebo-controlled trial of glucosamine sulphate as an analgesic in osteoarthritis of the knee. Rheumatology (Oxford).2002;41:279-284.

    8. Reginster JY, Deroisy R, Rovati L, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet. 2001;357:251-256

    9. Thie NM, Prasad NG, Major PW. Evaluation of glucosamine sulfate compared to ibuprofen for the treatment of temporomandibular joint osteoarthritis: a randomized double blind controlled 3 month clinical trial. J Rheumatol. 2001;28:1347-1355.

    10. Nguyen P, Mohamed SE, Gardiner D, et al. A randomized double-blind clinical trial of the effect of chondroitin sulfate and glucosamine hydrochloride on temporomandibular joint disorders: a pilot study. Cranio. 2001;19:130-139.

    11. Reginster JY, Deroisy R, Rovati L, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial.Lancet. 2001;357:251-256.

    12. Lippiello L, Woodward J, Karpman R, et al. In vivo chondroprotection and metabolic synergy of glucosamine and chondroitin sulfate. Clin Orthop. 2000;:229-240.

    13. Lippiello L, Karpman RR, Hammad T. Synergistic effect of glucosamine HCL and chondroitin sulfate on in vitro proteoglycan synthesis by bovine chondrocytes. Presented at: American Academy of Orthopaedic Surgeons 67th Annual Meeting; March 15-19, 2000; Orlando, Fla.

    14. Das A Jr and Hammad TA. Efficacy of a combination of FCHG49 glucosamine hydrochloride, TRH122 low molecular weight sodium chondroitin sulfate and manganese ascorbate in the management of knee osteoarthritis. Osteoarthritis Cartilage. 2000;8:343-350. 45. Drovanti A, Bignamini AA, Rovati AL. Therapeutic activity of oral glucosamine sulfate in osteoarthrosis: a placebo-controlled double-blind investigation. Clin Ther. 1980;3:260-272.


    Frequently Asked Questions - Bone, Joint, and Musculoskeletal

    • What is arthritis?

      There are many from of arthritis. Common arthritis symptoms are inflammation, pain, and stiffness of the joints.

    • What is Glucosamine?

      Glucosamine is a type of sugar produced in the body; it is an important building block of joint cartilage. As a supplement, glucosamine is most often used to ease the joint pain caused by arthritis or osteoarthritis. Glucosamine provides the raw materials needed to strengthen cartilage and attract water into the joint space for lubrication and smoothness.

      When delivered into the joint, glucosamine binds to cartilage to help build a compound called glycosaminoglycan, the main structural component of cartilage. Other evidence shows glucosamine may help cartilage cells called chondrocytes, to produce new cartilage and renew joint function.

    • What is Chondroitin?

      Chondroitin is a substance that occurs naturally in the connective tissues of the body. Chondroitin supplements are a popular answer for osteoarthritis.

    • Where are glucosamine and chondroitin sourced from?

      We offer both vegetarian and shellfish sources of glucosamine in our line. The shellfish source is a natural extract derived from multiple shellfish species and is comprised of a glucose molecule and the amino acid glutamine. The vegetarian form is sourced from corn, but is guaranteed to be free from corn allergens.


      Chondroitin sulfate is a natural extract from bovine cartilage and is a glycosaminoglycan which makes up the base substance in the connective tissue matrix. We use premium quality, USP chondroitin.

    • How is it possible to make a vegetarian glucosamine?

      Our Vegetarian Glucosamine uses a plant source form of glucosamine. It is made by taking dextrose from corn and fermenting it with a fungus called Aspergillus niger to create a vegetarian form of glucosamine hydrochloride. The final product is tested using Polymerase Chain Reaction (PCR) testing to ensure the absence of any corn DNA or allergens. This makes Vegetarian Glucosamine safe for vegetarians, those with shellfish allergies and people sensitive to corn.

    • How much glucosamine and chondroitin are recommended for those with joint health concerns?

      1,500 mg glucosamine and 1,200 mg chondroitin per day has been used in most of the research studies for joint conditions.

    • Should I take glucosamine with a meal?

      Yes. For maximum effectiveness, glucosamine should be taken with a meal.

    • How long will it take for me to feel positive results?

      The benefits of glucosamine supplementation develop over time. Generally, it may take 2 to 8 weeks before you see noticeable results

    • Are there any side effects or drug interactions with glucosamine?

      There are no significant side effects when taking glucosamine. There have been reports of minor upset stomach and heartburn in some individuals. People who are highly allergic to seafood should use caution before taking glucosamine. There are no known drug interactions.

    • Does glucosamine cause insulin resistance?

      According to published research, glucosamine does not worsen insulin resistance

    • Are there any contraindications for taking Joint Support Softgels before surgery?

      YES — fish oil is a natural blood thinner and bromelain may also act to thin the blood. Therefore, it is suggested to stop consuming fish oil a few weeks before anticipated surgery.

    • Can I take glucosamine if I have diabetes?

      In general, yes. Research suggests that taking glucosamine will not trigger or aggravate insulin resistance or high blood sugar. However, people with diabetes should take prudent caution and consult a physician before taking glucosamine

    • Does glucosamine affect cholesterol?

      A Journal of Nutrition study stated that there was an increase in cholesterol in male mice (with a 20 week consumption) but appeared to be safe overall and there were no complications of atherosclerosis with longer usage

    • What is the benefit of Glucosamine Chondroitin MSM?

      Glucosamine, Chondroitin, and MSM are three of the most powerful tested dietary ingredients for cartilage and joint tissue health.

    • Isn’t it true that glucosamine hydrochloride is an inferior, less useful form of glucosamine than the sulfate?

      Not at all. It is the glucosamine part of the molecule, not hydrochloride or sulfate that makes up the glycosaminoglycans and proteoglycans which help to form cartilage. What they are bonded to does not necessarily matter. According to the 2001 Physician’s Desk Reference for Nutritional Supplements (1st Ed.), “the counter union of the glucosamine salt (i.e. chloride of sulfate) is unlikely to play any role in the action or pharmokinetics of glucosamine.” In fact, the glucosamine content of the hydrochloride form is typically higher than that of the sulfate. Glucosamine hydrochloride is typically 83% in glucosamine base as opposed to 65% in sulfate.

    • What is MSM and where does it come from?

      MSM (technically known as methylsulfonylmethane) is a byproduct of DMSO, which comes from wood pulp and paper manufacturing. Much of the benefit of DMSO is thought to be from the actual amount of MSM occurring in it. MSM provides over 34% sulfur, which is considered the “active constituent.” Sulfur, one of the top eight essential minerals, is found in larger amounts in high protein foods. Much of the sulfur in plant foods is lost during processing. MSM is odorless and has a safe toxicity report. Our formula, MSM (OptiMSM®) is made from the finest quality of MSM

    • If sulfur is found in all plant and animal cells, why take an MSM supplement?

      Sulfur is one of the most common substances found in the body. Each and every one of our cells utilizes sulfur (the active constituent of MSM) to maintain cellular structure. The highest concentrations of sulfur are found in the joints, hair, skin and nails. Sulfur is also essential for proper enzymatic activity and hormone function.


      Even though MSM occurs naturally in the cells of all plants and animals, the mineral content in foods is affected by many factors. Geological conditions, soil condition from pesticide and fertilizer use, and the cooking process all contribute to the depletion of the natural sources of sulfur from the food supply.

    • How many types of Collagen are there?

      Currently 28 types of collagen have been identified. But over 90% of collagen in the body is Type I.

      The five most common types of collagen are:

      - Collagen Type I: found in skin, tendons, artery walls, scar tissue, eye (cornea) organs, even in the organic parts of bone and teeth.
      - Collagen Type II: this is the main component of cartilage (about 50% of cartilage is type II collagen).
      - Collagen Type III: This is commonly found alongside type I collagen as it is a connective (reticular) tissue. It is also found in skin, intestines, uterus, and artery walls.
      - Collagen type IV: found in the eye lens and as an outside surface on cells (basal lamina).
      - Collagen Type V: is associated with Type I, and is found on cell surfaces, hair and placenta.

      Collagen is essential for the structure and function of connective tissues, which bond other tissues and organs together. Collagen is also the most integral part of the skin’s fabric and naturally forms its mesh-like structure. Aging is closely associated with the loss of collagen and the deterioration of connective tissues; therefore, supplementation with collagen can help to counteract these negative consequences.

      In addition to three types of collagen, our Regenerage Collagen Complete product provides glycosaminoglycans (GAGs) such as hyaluronic acid and chondroitin sulfate. GAGs are required for healthy structure and function of connective tissues, including joints and the skin dermis

    • Is the chicken cartilage used in Super Joint Complex hormone free?

      Yes it is hormone free, with a statement on file from our raw material suppliers.

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