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PRODUCT SUMMARY

Antioxidant - Alpha-Lipoic Acid 300 mg Veg Caps (60 Count)

Availability: In stock
Stock Number :AOX-315-VC-060
  • Healthy Aging
  • Eye Health and Visual Support
  • Energy Support
  • Liver Support
  • Weight Management
  • Quick Notes:

    • Alpha Lipoic acid is a potent antioxidant that helps combat free radicals in the body.
    • Water Soluble and Fat Soluble antioxidant, providing antioxidant protection inside

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    List Price: $35.27

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    Product Information

    Quick Notes:

    • Alpha Lipoic acid is a potent antioxidant that helps combat free radicals in the body.
    • Water Soluble and Fat Soluble antioxidant, providing antioxidant protection inside the cell wall, as well as in the intracellular spaces
    • Alpha Lipoic acid is an essential cofactor of several energy producing reactions.
    • Recycles CoQ10, Vitamin C, Vitamin E, and glutathione in the body.
    • Maintains blood sugar levels as part of a healthy diet.
    • Convenient, easy-to-swallow capsules!

    Overview:

    Our Alpha Lipoic Acid is available in vegetarian capsules. Alpha lipoic acid is also known as thioctic acid; a powerful antioxidant. It exists as an enzyme in the mitochondria (cell's powerhouse). Alpha Lipoic Acid is also involved in recycling other antioxidants like vitamin C and vitamin E, thereby increasing their potency. Alpha Lipoic Acid is often referred to as a “universal antioxidant” because it is more effective at neutralizing free radicals than most other antioxidants. Alpha Lipoic Acid is active in both water based regions and fatty areas of the body. Most other antioxidants are active in either one or the other. ALA helps in glutathione recycling which is another important antioxidant. Along with B vitamins, ALA helps in energy generation from carbohydrate, protein, and fat metabolism.

    Research indicates:

    • Acts as a powerful antioxidant
    • Supports healthy glucose metabolism
    • May support healthy energy levels
    • Used by professionals in the treatment of nerve damage
    • Assists enzymes in conversion of food to energy
    • May support healthy liver function
    • Studies indicate may be used in prevention of cataracts
    • May support healthy immune function

    Ingredients

    Alpha Lipoic Acid

    Suggested Use:

    Take one capsule up to two times daily with food.

    Storage:

    Keep in a cool, dry place.

    Allergy Warnings:

    This product is contraindicated for individuals with hypersensitivity to any of its ingredients.

    Interactions:

    • Everyone has unique body chemistry. All patients should be aware of potential drug and supplement interaction. You are encouraged to consult with your primary health care professional before taking any supplement product.

    • Alpha Lipoic Acid occasionally causes mild gastrointestinal discomfort when taken in doses exceeding 3000 mgs; taking with a meal usually eliminates this reaction. Discontinue use and consult a health care practitioner if symptoms worsen or persist.

    Pregnancy Warning:

    If you are pregnant, nursing, have any health condition, or are taking any medications please consult with your health care practitioner before using this product.

    Keep out of reach of children.

    Disclaimer:

    • The following scientific literature references, articles, and statements have not been evaluated by the Food and Drug Administration (FDA).
    • This product is not intended to treat, cure or prevent any disease.
    • Information about this product is intended for your general knowledge only and is not a substitute for professional medical advice or treatment.
    THANKS!
     1. Beitner H. Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin.Br J Dermatol. 2003;149:841-849.

    2. Melhem MF, Craven PA, Liachenko J, et al. Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes. J Am Soc Nephrol. 2002;13:108-116

    3. Ziegler D, Gries FA. Alpha-lipoic acid in the treatment of diabetic peripheral and cardiac autonomic neuropathy. Diabetes. 1997;46(suppl 2):S62-S66.

    4. Packer L, Witt EH, Tritschler HJ. Alpha-lipoic acid as a biological antioxidant. Free Radic Biol Med. 1995;19:227-250.

    5. Jacob S, Henriksen EJ, Schiemann AL, et al. Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid. Arzneimittelforschung. 1995;45:872-874.

    6. Nagamatsu M, Nickander KK, Schmelzer JD, et al. Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care. 1995;18:1160-1167.

    7. Kagan VE, Shvedova A, Serbinova E, et al. Dihydrolipoic acid—a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl, and chromanoxyl radicals. Biochem Pharmacol. 1992;44:1637-1649.

    FAQ

    Frequently Asked Questions - Antioxidants & Health Aging

    • What are free radicals and antioxidants?

      Antioxidants provide the body with protection from potentially damaging compounds called free radicals. Free radicals are highly reactive chemicals with unpaired electrons that steal electrons from other molecules, causing a vicious chain reaction that wreaks havoc on the body. Free radicals can damage the body’s tissues and may increase the risk of negative health issues. 

      Free radicals are normal by-products of metabolism, normal physiological processes, as well as environmental toxins like air pollution, ozone, chemicals, drugs, cigarette smoke, radiation, heavy metals, pesticides, and especially in defense against microbes and other foreign substances. 

      Antioxidants provide preventive care to the body, protecting against the negative health consequences that can result from free radical damage. They scavenge or neutralize free radicals, stopping the free radical chain. Antioxidants can be found in a variety of foods, with higher amounts in plant foods. Many supplements are available on the market to help ensure the body receives an adequate amount of antioxidants daily. 

      Some of these traditional antioxidants include:

      • Natural vitamin E (d-alpha tocopherol)

      • Vitamin C

      • Beta-Carotene (provitamin)

      • Selenium

      Antioxidants that are available through the diet are considered exogenous antioxidants and include: amino acids [N-acetyl-L-cysteine (NAC), taurine and L-glutathione (tripeptide)], vitamins C and E, carotenoids (beta-carotene, lycopene, lutein and zeaxanthin), and minerals (selenium and zinc).  Antioxidants produced in the body are considered endogenous antioxidants and include: ubiquinone/ubiquinol (CoQ10), alpha lipoic acid, the master cellular defense enzyme, superoxide dismutase (SOD), and many more.

      However, many factors have been found to compromise the levels of endogenous antioxidants in the body making supplementation essential (for example: normal aging process, certain medications and oxidative stress).

    • What does neutralizing "free radicals" in the body mean?

      Free radicals are highly reactive compounds produced spontaneously in the body or because of exposure to certain pollutants. They can be dangerous, since they cause damage to body cells and tissues, including genetic material. Recent studies indicate that vitamins C, E, beta-carotene, and several other products characterized as antioxidants protect against free radical damage hence the term neutralizing free radicals. 

    • How much caffeine is in Advanced Antioxidant Complex?

      There is less than 1.5 mg caffeine per vegetarian capsule. Comparatively, one cup of tea provides about 50 mg of caffeine per cup.

    • Is the Alpha-Lipoic Acid in the “R” form?

      The Alpha-Lipoic Acid is 50% R form and 50% S form.

    • What is the source of Alpha-Lipoic Acid?

      The Alpha-Lipoic Acid is synthetically made, but nature identical. 

    • Why don’t you use the pure R form of Alpha- Lipoic Acid (ALA)?

      Some ALA products are in the “R” form (natural) and some are in the “S” form. The S form is an isomer, or mirror image. Our Alpha-Lipoic Acids are an equal mix (racemic mix) of both R and S. Some references claim that the R is more potent; however studies done using ALA showing benefit to blood sugar, etc. use the racemic mix. According to the PDR for Nutritional Supplements, 2001, “the natural R-enantiomer is more readily absorbed than the L-enantiomer and is the more active form...some studies showing significant antioxidant effects have used doses of the racemic mixture of 600 mg daily.” At this time, there isn’t a significant volume of human studies using the pure R form against the S form (although a few animal and in vitro ones exist) to make valuable conclusions for human dosage.

    • Alpha lipoic acid, are there two kinds?

      Alpha lipoic acid or thioctic acid is a natural antioxidant that has gained substantial attention from the scientific community for its involvement in energy production (formation of adenosine triphosphate – ATP) from the metabolism of fats, carbohydrates and proteins. Like most compounds in the body, lipoic acid has an asymmetrical carbon atom, which produces a mirror image and exists in nature as two forms (enantiomers). The forms are designated as either R or S depending on their structural relationship to a right- or left-handed reference point. While both forms are found in biological systems, lipoic acid is represented as the R-form when active. Alpha Lipoic Acid is a 50/50 mixture of both the R- and S- forms of the molecule.  Our formula provides Alpha Lipoic Acid is 50% R form and 50% S form.

    • What is Coenzyme Q10 (also called ubiquinone or ubiquinol) and how does it function in the body?

      CoQ10 is synthesized in every cell of the body. It is naturally present in small amounts in foods, but is particularly high in organ meats such as heart, liver and kidney and levels decline with age.

      To consume just 30 mg of CoQ10, you would have to eat one of the following:

      • 1 pound sardines

      • 2 pounds of beef

      • 2.5 pounds of peanuts 

    • What is the source of CoQ10?

      It is a fermentation product from yeast. This process ferments glucose and inorganic acid on bacteria.

    • What gives CoQ10 products their orange color?

      That is the natural color of CoQ10. No food coloring or other ingredients are added.

    • How and when should I take CoQ10?

      CoQ10 works better if taken with fats and oils. All forms of CoQ10 will work better if taken with a meal containing fats, or with healthy supplements providing fat, such as fish oil, flax oil, coconut oil, etc.

    • How can you determine how much CoQ10 to take?

      CoQ10 levels are concentrated in certain tissues such as the heart and muscles that use it, so you would have to do a biopsy of that tissue (not a good idea) to determine CoQ10 levels in the body. Scientific studies use certain doses in human subjects to determine effectiveness for a given condition. This is the best way to ascertain how much to take — once approved by your healthcare practitioner, of course.

    • Are there any interactions with CoQ10 and Coumadin (warfarin)?

      According to the PDR (Physician’s Desk Reference) for Nutritional Supplements, 2001, there is one report of CoQ10 decreasing the effectiveness of warfarin (Coumadin).

    • What is the difference between ubiquinol vs. ubiquinone?

      Our CoQ10 products are in the ubiquinone form. Ubiquinol is a form also found in the body — a stabilized form was launched in 2006 by a Japanese company for use in dietary supplements. A few studies show enhanced absorption with ubiquinol in the first 24 hours, but after more than one day the plasma levels achieved are identical between the two forms. 

      Ubiquinone (CoQ10) has significant antioxidant activity in the membrane portion of the mitochondria in the cell. Ubiquinone is reduced to ubiquinol (active form) as a normal process in the mitochondria to fight against the free radicals. Ubiquinone is effective in antioxidant capability and has over 30 years of research in various disease states.

    • How much caffeine does Leucoselect® Grape Seed Extract contain per tablet?

      Each tablet contains only approximately 1.5 mg of caffeine. By comparison, a single cup of coffee contains 120-240 mg.

    • What plant species is used for Leucoselect® Grape Seed Extract?

      The grape seeds come from Chardonnay grapes (Vitis vinifera) grown in France.

    • What are the components in the antioxidant Pycnogenol® and from where are they obtained?

      Pycnogenol® is a potent antioxidant (free radical scavenger) that is extracted from the bark of a specific variety of pine that grows in Southern France. It contains over 40 water soluble antioxidants and is composed primarily of proanthocyanin, a subclass of antioxidants.

       

      As determined by the Porter Method, the most accurate methodology available to specifically quantify proanthocyanidincontent, Pycnogenol® yields:

      • 3% water

      • 15% catechin and epicatechin (monomers)

      • 17% organic acids, organic acid glucosides and glucose esters

      • 65% proanthocyanidins

    • How many glasses of red wine would you have to drink in order to get 150 mg of resveratrol — the amount in your Resveratrol 150 mg?

      To get 150 mg of Resveratrol, you’d have to drink 79-500 (5-oz) glasses of red wine. That’s equivalent to about 15-100 bottles of red wine (assuming there is 25 floz in a bottle of wine). Please drink responsibly! 

    • What is the difference between trans-form versus cis form in Resveratrol 150 mg?

      The trans-form exists in grapes and peanuts. The cis form is created once you heat or irradiate the substance. The structural formula changes to a different arrangement of atoms but it is the same molecular formula.

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